Design and synthesis of astatinated benzothiazole compounds for their potential use in

      Targeted Alpha Therapy (TAT) strategies to treat Alzheimer’s disease-associated amyloid plaques

      Emily K. Kirkeby, Chyan, M.-K.; Diehl, G.; Wilbur, S.; Li, Y.; Roberts, A. G.;* Mastren, T.*

      in preparation, 2022

12. An amine template strategy to construct successive C–C bonds:

      Synthesis of benzo[h]quinolines by a deaminative ring contraction cascade

      McFadden, T. P.; Nwachukwu, C. I.; Roberts, A. G.*

      Org. Biomol. Chem. 2022,

      DOI: 10.1039/D1OB02245H

11. Creating a Natural Vascular Scaffold by Photochemical Treatment

      of the Extracellular Matrix for Vascular Applications

      Kauser, K.;* Warner, K. S.; Anderson, B.; Keyes, E. D.; Hayes, R. B.; Kawamoto, E.; Perkins, D. H.;

      Scott, R.; Isaacson, J.; Haberer, B.; Spaans, A.; Utecht, R.; Hauser, H.; Roberts, A. G.; Greenberg, M.

      Int. J. Mol. Sci. 2022, 23, 683.

      DOI: 10.3390/ijms23020683

10. New Role for Radical SAM Enzymes in the Biosynthesis of Thio(seleno)oxazole RiPP Natural Products.

      Lewis, J. K.; Jochimsen, A. S.; Lefave, S. J.; Young, A. P.; Kincannon, W. M.;

      Roberts, A. G.; Kieber-Emmons, M. T.;  Bandarian, V.* 

      Biochemistry 2021, 60, 3347 – 3361.

      DOI: 10.1021/acs.biochem.1c00469

9.  Photosensitized Oxidative Dimerization at Tyrosine by a Water-Soluble 4-amino-1,8-naphthalimide.

     Keyes, E. D.; Kauser, K.; Warner, K. S.; Roberts, A. G.*

     ChemBioChem2021, 22, 2703 – 2710.

     DOI: 10.1002/cbic.202100193

8.  Design, synthesis and characterization of structurally dynamic cyclic N,S-acetals.

     Kirkeby, E. K.; Roberts, A. G.*

     Chemical Communications2020, 56, 9118 – 9121.

     DOI: 10.1039/D0CC03503C
       (a) 2020 Emerging Investigators (link) (Chem. Commun., special issue)

       (b) Arora P and Brown G: Faculty Opinions Recommendation of [Kirkeby EK and Roberts AG, Chem Commun (Camb) 2020].

            In Faculty Opinions, 10 Aug 2020; 10.3410/f.738380854.793577286


7.  Ni-catalyzed iterative alkyl transfer from nitrogen enabled by the in situ methylation of tertiary amines.

     Nwachukwu, C. I.; McFadden, T. P.; Roberts, A. G.*

     Journal of Organic Chemistry2020, 85, 9979  9992.


     DOI: 10.1021/acs.joc.0c01274


mentored research.

6.  Cascading auto-oxidative biproline guanylations form optically active dispacamide dimers and permit an eight-step         synthesis of (–)-ageliferin.

     Ding, H.; Roberts, A. G.; Chiang, R.; Harran, P. G.

     Journal of Organic Chemistry, 2018, 18, 7231 – 7238.


     DOI: 10.1021/acs.joc.8b00631

        (a) Synthesis of Antibiotics and Related Molecules (J. Org. Chem., Special Issue)

        (b) Synthesis of Antibiotics and Related Molecules (J. Org. Chem., Editorial)

             Movassaghi, M.; van der Donk, W. A. J. Org. Chem. 2018, 83, 6826.

5.  Total Chemical Synthesis and Folding of all-L and all-D Variants of Oncogenic KRas(G12V).

     Levinson, A. M.‡; McGee, J. H.‡*; Roberts, A. G.‡*; Creech, G. S.; Wang, T.; Peterson, M. T.;                       

     Hendrickson,R. C.; Verdine, G. L.; Danishefsky, S. J.*   

     Journal of the American Chemical Society, 2017, 139, 7632 – 7639.   

     DOI: 10.1021/jacs.7b02988

        (a) highlight from Memorial Sloan Kettering Cancer Center

        (b) Tri-Institutional Program in Chemical Biology (TPCB) covers Dr. Levinson's thesis research!

        (c) Dr. Adam M. Levinson's PhD Thesis (2017)

4.  Fully Synthetic Granulocyte Colony-Stimulating Factor (G-CSF) Enabled by Isonitrile-Mediated Coupling of Large,           Side-Chain Unprotected Peptides.

     Roberts, A. G.‡*; Johnston, E. V.‡; Shieh, J-H.; Sondey, J. P.; Hendrickson, R. C.;

     Moore, M. A. S.; Danishefsky, S. J.*

     Journal of the American Chemical Society, 2015, 137, 13167 – 13175.

     DOI: 10.1021/jacs.5b08754

        (a) F1000 Prime recommended article

        (b) highlight at Organic Chemistry Portal

3.  Total Synthesis of Ageliferin via Acyl N-amidinyliminium Ion Rearrangement.

     Ding, H.‡; Roberts, A. G.‡; Harran, P. G.*

     Chemical Science,  2013, 4, 303 – 306.


      DOI: 10.1039/C2SC21651E


2.  Synthetic (±)-Axinellamines Deficient in Halogen.

     Ding, H.; Roberts, A. G.; Harran, P. G.*

     Angewandte Chemie International Edition, 2012, 51, 4340 – 4343. (VIP paper)


     DOI: 10.1002/anie.201200205 

1.  Exploring Symmetry-Based Logic for a Synthesis of Palau’amine.

     Li, Q.; Hurley, P.; Ding, H.; Roberts, A. G.; Akella, R.; Harran, P. G.*

     Journal of Organic Chemistry, 2009, 74, 5909 – 5919.

     DOI: 10.1021/jo900755r

    Ph.D. Thesis.

    Symmetry-Based Access to Polycyclic Bis-guanidines: Total Synthesis of (±)-Ageliferin

    and the Complete Axinellamine Ring System.

     by Roberts, A. G., Ph.D., University of California, Los Angeles, 2013, 1 – 482.


     UMI Number: 3592856 

* corresponding author ‡ equal contribution

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